BCHM G4021x. General Biochemistry. 3 pts.

Primarily for students in departments other than biochemistry. Prerequisite: general and organic chemistry. An integration, from a dynamic point of view, of cellular constituents with the chemical processes of living systems: chemistry and function, mode of synthesis and degradation by the cell, the characterization and role of particular enzymes and coenzymes in these reactions, and the mechanisms of oxidation and energy production. Nucleic acids, replication, and the genetic code are also discussed. (Given at the Morningside campus.)

BCHM G4024y. Structure and Function of Nucleic Acids. 4 pts. Not offered in 2009-2010. Prerequisite: organic chemistry. The structure, dynamics, catalytic reactivity and biological function of DNA, RNA, and their derivatives

BCHM G4026y. Biochemistry of Nucleic Acids and Protein Synthesis. 3 pts. Prerequisites: a basic course in biochemistry or biology, or instructor's permission. Structure and organization of chromatin, nucleic acid hybridization, and sequence complexity of DNA, DNA and RNA sequencing methods, current views of replication and repair, transcription and translation, regulation of nucleic acid and protein syntheses, recombinant DNA techniques, gene transfer and gene duplication. Discussion of original papers and evaluation of experimental procedures and conclusions. Lectures preceded by an hour-long optional conference. (Given at the Morningside Campus.)

BCHM G6011x-G6012y. Special Methods of Biochemistry. 2-10 pts. Prerequisite: department's permission. Practical experience in the use of biochemical methods, with the aim of preparing the student for research.

BCHM G6100x. Stem Cells & Cell Lineage Specification. 3 pts. Not offered in 2009-2010. Prerequisites: A basic course in molecular biology or permission of the instructor.

The lecture series will comprise general lectures, analyses and discussion of primary literature on stem cell and lineage biology as well as student seminars. The themes to be presented include basic cell and molecular biological charachterization of stem cells, regulation of self-replication versus lineage restriction and differentiation of cells, model systems used in studies of stem cells, and the relevance of tissue formation, regeneration and disease states.

BCHM G6270y. Nmr Spectroscopy of Macromolecules. 4 pts. Prerequisites: instructor's permission or Biophysical Chemistry G4170.

Theoretical principles and applications of NMR spectroscopy for the study of biological macromolecules, including proteins, nucleic acids and carbohydrates, in solution.

BCHM G6275y. Diffraction Analysis of Macromolecules. 4.5 pts. Prerequisites: Biophysical Chemistry G4170 or the instructors' permission.

Diffraction theory and applications to protein, nucleic acid, and membrane structures. Topics include electron microscopy, X-ray diffraction, protein crystallography, electron and neutron diffraction and electron microscopy.

BCHM G9015x-G9016y. Research In Biochemistry. 2-10 pts.

Prerequisite: instructor's permission